Undergraduate Course Descriptions

   CBN Courses (subject code 146):

01:146:201-202 Independent Study in Cell Biology and Neuroscience (1-3,1-3) Independent study under the direction of a member of the faculty. Written report required. Prerequisites: Permission of the Department and instructor willing to sponsor the student, and a cumulative grade-point average of 2.8 or better. May not be used to fulfill a laboratory requirement. Open only to students majoring or planning to major in cell biology and neuroscience. (Fall, Spring)

01:146:245 Fundamentals of Neurobiology (3) Introduction to the biology of the nervous system. Topics covered include nerve cell signaling, sensory and motor systems, and higher brain processes. Prerequisites: General Biology (01:119:115-116 or 01:119:101-102). (Fall, Spring, Summer)

01:146:270 Fundamentals of Cell and Developmental Biology (3) Principles of cell biology. Structure, function, and macromolecular organization of cellular organelles. Prerequisites: General Biology (01:119:115-116 or 01:119:101-102). (Fall, Spring, Summer)

01:146:295 Essentials of Cell Biology and Neuroscience (3) Topics range from regulation of gene transcription to neural signaling and cognition with a focus on how this information can be applied to remediation of neurological disorders. Prerequisites: General Biology (01:119:115-116 or 01:119:101-102). Not for Cell Biology and Neuroscience majors. (Fall, Spring)

01:146:307-308 Research in Cell Biology and Neuroscience (1-3,1-3) Laboratory Research on original problem under the direction of a member of the faculty. Written report required. Prerequisites: Permission of the Department and instructor willing to sponsor the student, and a cumulative grade-point average of 2.8 or better. Open only to students majoring or planning to major in cell biology and neuroscience. (Fall, Spring)

01:146:310 Physiological Adaptation: Heart, Stress, and Exercise (3) An integrative approach to physiology. Understanding of the body's ability to adjust and adapt to internal and external environmental challenges in an historical perspective.   Open to students in the Honors College and SAS honors program.  Credit not given for both this course and 01:119:194.  Prerequisite: 01:119:115, 01:119:116

01:146:322 Human Histology (4) Structure of the tissues and organs of the animal body. Lec. 3 hrs., lab. 3 hrs. Prerequisite: General Biology (01:119:117 or 01:119:102) and Fundaments of Cell and Developmental Biology (146:270) or 01:146:295. (Spring)

01:146:328 Human Parasitology (3) Discussion of the cell biology, epidemiology, pathogenesis, and clinical manifestations of human parasitic diseases. Lec. 3 hrs. Prerequisites: General Biology (01:119:115-116 or 01:119:101-102). (Fall, Spring, Summer)

01:146:329 Human Parasitology Laboratory (1) Laboratory to accompany Human Parasitology (01:146:328). Lab. 3 hrs. Prerequisite: General Biology (01:119:117 or 01:119:102); Corequisite: Human Parasitology (01:146:328). (Fall, Spring, Summer)

01:146:340 Virology (3) A discussion of the principles of virology that will include an in depth look at the molecular and cellular events that occur during virus replication, the host cell response, and pathogenesis. Emphasis will be placed on animal viruses that impact human health and disease. Strategies for controlling viruses and factors influencing the emergence of new viruses will also be addressed. Prerequisites: Genetics (447:380) or Fundamentals of Cell Biology (146:270). (Fall; even years only)

01:146:356 Systems Physiology (3)
Comprehensive study of the principal organ systems of laboratory animals and humans. Prerequisites: General Biology (01:119:115-116 or 01:119:101-102) and General Chemistry (01:160:161-162) or Honors General Chemistry (01:160:163-164) and Intr Exprimentation (01:160:171). Credit not given for both this course and Animal Physiology Lab (11:067:300). (Fall, Spring, Summer)

01:146:357 Systems Physiology Laboratory (1) Laboratory to accompany System Physiology (01:146:356). Lab. 3 hrs. Prerequisite: General Biology (01:119:117 or 01:119:102); Corequisite: System Physiology (01:146:356). (Fall, Spring)

01:146:405 Honors Seminar (3) Development of communication and written skills needed by professionals in cell biology and neuroscience. Oral reports, written papers, and discussion of topics of current interest in the field. Prerequisite: Permission of department. Open only to senior CBN honors students. (Spring)

01:146:406-407 Research in Cell Biology and Neuroscience (1-4,1-4) Research under the direction of a member of the departmental faculty. Written report required. Prerequisites: Permission of the Department and instructor willing to sponsor the student, and a cumulative grade-point average of 2.8 or better. Open only to students majoring in cell biology and neuroscience. (Fall, Spring)

01:146:408-409 Honors Research (3-6,3-6) Research project under the direction of a departmental faculty member. Written report and oral presentation required. Prerequisites: Permission of the Department and instructor willing to sponsor the student. Open only to seniors majoring in Cell Biology and Neuroscience who meet the requirements for the departmental honors program. (Fall, Spring)

01:146:445 Advanced Neurobiology I (3) Advanced concepts in neurobiology focusing on cellular and molecular aspects of neuronal signaling, including ion channel gating, sensory transduction, and transmission across chemical and electrical synapses. Prerequisite: General Biology (01:119:117 or 01:119:102 and Fundamentals of Neurobiology (146:245) and Fundamentals of Cell Biology (146:270). (Fall)

01:146:446 Advanced Neurobiology Laboratory I (3) Advanced laboratory methods in neurobiology. Electrophysiological and immunochemical techniques to explore the structural and functional features of nerve cells. Prerequisites: Advanced Neurobiology I (01:146:445) and permission of instructor. (Spring)

01:146:447 Advanced Neurobiology II (3) A course in the neurobiology of disease. It will have four components, each of which will be taught as a separate module: developmental disorders, injury to brain and spinal cord, regeneration and neurodegenerative diseases including Alzheimer's disease. Prerequisites: General Biology (01:119:117 or 01:119:102) and Fundamentals of Neurobiology (01:146:245) and Fundamentals of Cell Biology (01:146:270). (Spring)

01:146:448 Advanced Neurobiology Laboratory II (3) Advanced laboratory methods in molecular neurobiology. Study of neuronal differentiation, neurite outgrowth, and neuronal protein trafficking using molecular biological, cell biological, and biochemical techniques. Prerequisites: Advanced Neurobiology I (01:146:445) and permission of instructor. (Spring)

01:146:450 Endocrinology (3) This course covers the structure and function of the endocrine and neuroendocrine glands and the biosynthesis and chemistry of the hormones produced by them. In addition, this course will integrate basic and clinical aspects of endocrinology, with a view to enhancing an understanding of the consequences of diminished and excessive production of individual hormones.  Prerequisites: 01:119:115-116.  Credit not given for both this course and 11:067:450. (Fall)

01:146:456 Advanced Physiology (3) Open only to senior and junior CBN majors.  Preparation for advanced graduate study in physiology and for medical physiology (first year medical school).  Focus on mammalian physiology and the whole animal (whole organ) approach.  Prerequisite:  01:146:356


01:146:464 Stem Cell and Spinal Cord Injury (Section 1 in Topics in Cell Biology and Neuroscience) (3) Directed readings and discussion of selected topics in cell biology and neuroscience. Prerequisites: Fundamentals of Neurobiology (146:245) and Fundamentals of Cell Biology (146:270). (Fall)

01: 146:464 Brain and Inner Ear Cell Development and Function (Section 2 in Topics in Cell Biology and Neuroscience) (3)
This is a 3-credit course open to CBN majors in their junior or senior years (18 students maximum). The course will have three modules focused on three neuroscience topics. Each module consists of faculty lectures and student presentations.  Each student will also be required to write a brief critical review of the assigned research paper. Topics include mammalian brain development, inner ear cell development, and function of cortical circuits. Prerequisites: 146:245 and 146:270, AND at least 1 Advanced course (01:146:445, 01:146:447, 01:146:470 or 01:146:472) and 1 research course (01:694:214, 01:146:448, 01:146:471, 1 semester of 01:146:201-202, 01:146:307-308, 01:146:406-407 or 01:146:408-409). (Spring)

01:146:464 Neuron/Glia Signaling Mechanisms in Neurodevelopment and Neurodegeneration (Section 3 in Topics in Cell Biology and Neuroscience) (3)
This is a 3-credit course open to CBN majors in their Junior and Senior years. The course will have three modules focused on electrophysiological, trophic, intracellular signaling and quality control mechanisms in neurons and glia cells underlying nervous system function and dysfunction. Each module consists of a mixture of lectures by the teaching faculty and student presentation/discussion of assigned primary research articles. Each student will also be required to write a brief critical review of the assigned research papers. Prerequisites: Fundamentals of Neurobiology (146:245) and Fundamentals of Cell Biology (146:270), plus at least 1 Advanced course (Advanced Neurobiology I 01:146:445, Advanced Neurobiology II 01:146:447, Advanced Cell Bio 01:146:470 or Advanced Developmental Biology 01:146:472) and 1 hands-on research course (Research in CBN 01:146:307-308 or 1:146:406-407, Advanced Neurobiology Lab 01:146:448, Advanced Cell Bio Lab 01:146:471, 1 semester of Independent study 01:146:201-202 or Honors Research 01:146:408-409). (Fall)

01:146:464 Harnessing Immunity in Cancer and Disease (Section 4 in Topics in Cell Biology and Neuroscience)
 (3) This is a 3-credit directed reading and discussion course on cancer biology. Open to CBN majors in their Junior and Senior years. Prerequisites: Immunology, 146:474 (Spring).

01:146:470 Advanced Cell Biology (3) Advanced concepts of cell biology focusing on the molecular organization of cells, including internal membranes and synthesis of macromolecules, the cell nucleus, the cell cycle, cytoskeleton, cell-cell adhesion and the extracellular matrix, and signal transduction. Prerequisites: General Biology (01:119:117 or 01:119:102) and Fundamentals of Cell Biology (146:270 ). Credit not given for both this course and 01:119:370  or 01:119:378 or 01:146:370 (Fall)

01:146:471 Advanced Cell Biology Laboratory (3) Advanced laboratory methods in cell biology. Emphasis on microscopy, immunochemical techniques, bacterial and mammalian cell culture, and methods of identifying and separating macromolecules. Prerequisites: Advanced Cell Biology (01:146:470) and permission of instructor. (Spring)

01:146:472 Advanced Developmental Biology (3) Molecular biology of early development, morphogenesis, organogenesis, tissue interactions, and genetic control of cellular differentiation. Prerequisites: General Biology (01:119:117 or 01:119:102) and Fundamentals of Cell Biology (01:146:270). (Spring)

01:146:474 Immunology (3) Fundamental principles of immunology with emphasis on antibody formation, immunoglobulin molecules and genes, hypersensitivity reactions, and the cellular basis for the immune response. Prerequisites: General Biology (01:119:115-116 or 01:119:101-102) and Genetics (01:447:380) or Genetic Analysis (01:447:384). Recommended: General Microbiology (01:447:390). (Spring)

01:146:475 Laboratory in Immunology (1) Biochemical and molecular analysis of immune cell function. Application of immunological techniques to the examination of normal and diseased states. Prerequisite: General Biology (01:119:117 or 01:119:102); Corequisite: Immunology (01:146:474). (Spring)

01:146:478 Molecular Biology (3) Structure and function of macromolecules, recombinant DNA technology, and study of genes and their regulation at the molecular and cellular levels. Prerequisites: Organic Chemistry I (01:160:307) and Organic Chemistry II (01:160:308). For juniors and seniors only. Credit not given for both this course and Molecular Biology and Biochemistry (01:694:408) or Biotechnology (11:126:481). (Spring)



Please check the online Schedule of Classes to make sure that a course is being offered during the semester(s) indicated in parentheses.