Detail

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  • Peng Jiang
  • Associate Professor
  • pj221@rutgers.edu
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  • Phone: 848-445-2805
  • Office: B209 Nelson Labs
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  • Research Group: Neuroscience
  • Research Interests:

    Stem cells as a model of brain development and disease, stem cell regenerative medicine for neural repair
  • News Articles:
  • Dr. Peng Jiang's Research Could Help Lead to Down Syndrome Treatment
  • Current Research:

    The goal of our research is to create human induced pluripotent stem cell (hiPSC) neural differentiation models for studying the cellular and molecular basis of human neural development and pathogenesis of neurodevelopmental disease, and to develop stem cell regenerative medicine to treat neurological disorders. We have been developing hiPSC-based in vitro 2-dimensional (2D) neural differentiation and 3D CNS organoid models and in vivo human chimeric mouse brain models to investigate how abnormal gene expression in neurodevelopmental disorders, such as Down syndrome, causes abnormal brain development, changes synaptic plasticity, and leads to cognitive deficits in these disorders. In addition, hiPSCs hold great promise for developing cell therapies to replace damaged brain cells and restore brain functions after CNS injury. We also study how to derive functionally competent neural cells from hiPSCs for neural repair. The basic and translational stem cell research we are pursuing critically bridges between the understanding of human neural development in heath and disease, and the development of stem cell medicine to treat neurological disorders.
  • PubMed Publications:

     

    For CBN's main publication search, click here.
  • Research Summary:

    Stem cells as a model of brain development and disease, stem cell regenerative medicine for neural repair
  • Recruiting New Research Assistants: 2021-2022
  • Research Summary:

    Stem cells as a model of brain development and disease, stem cell regenerative medicine for neural repair
  • How to Apply:

    Email
  • Semesters Accepting Students:

    Fall: Maybe
    Spring: Maybe
    Summer: Maybe
  • Research Preferences:

    Students interested in graduate school, GPA 3.5+. Please email to apply. I, together with postdoctoral fellows and graduate students in the lab will screen and make decision.