The IN Cell Analyzer 6000 is the industry standard for a laser-based confocal imaging platform for high-content assays and screens. The platform enables automated high throughput image acquisition for a wide variety of multiwell plate assays. The system provides a quantitative image-based platform for cell counting, cell viability assays and morphometric analysis. The microscope has 4 laser lines (405, 488, 561 and 633nm), a variety of objectives (4X, 10X, 20X and 40X) and a sCMOS camera for acquiring large fields of view. A liquid dispenser and heating platform allows dispensing of compounds to the multiwell plate while acquiring images at physiological temperatures in live cells. The high content analysis software offers powerful analytics with a simple and intuitive interface using images acquired on the IN Cell Analyzer system.